Yes, many people buy websites from other countries and run them successfully. Just make sure the audience is mainly in the US if that's your target market.
 
You can definitely run a US-focused affiliate site while living in Europe. Plenty of people do exactly that.
 
Before buying, check whether the site's traffic comes mostly from the US. That's more important than where the seller lives.
 
I own websites targeting three different countries, and I manage all of them from one laptop.
 
The internet doesn't really care where you live. Focus on traffic quality and revenue stability instead.
 
I've been managing US affiliate sites from Germany for years without any problems.
 
Just make sure you can transfer the domain, hosting, analytics, and affiliate accounts smoothly.
 
One thing to check is whether the affiliate programs allow ownership transfers after the sale.
 
I've bought websites from the UK and Australia while living elsewhere. The transition was straightforward.
 
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