One thing I always check first is whether anything changed before the issue started. Even something that seems unrelated can sometimes influence how mailbox providers evaluate your campaigns.
 
I don't think PMTA itself is necessarily the issue. I'd probably spend more time reviewing sender reputation and campaign performance before making any software changes.
 
Deliverability has become much more challenging over the last couple of years. Mailbox providers appear to be placing greater emphasis on recipient satisfaction than ever before.
 
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